I ran nearly everyday for 30 years, literally. 5 years ago I had to quit because it took out my lower back. Although I rode bike my whole life, I started riding bikes seriously, averaging 7000 miles annually. Year and a half ago, started experiencing perineum pain. Riding caused inflammation, psa was higher, had surgery at Mayo a year ago. Helped, but long rides 20+ miles would irritate perineum. Bought a STR Expert, made since, big difference. I can take longer rides now without irritation. Age will get most all of us at some point. Only problem with the STR is I am limited to a 46 tooth chain ring. I would have liked to build a high-end road bike.